Home   -   Research   -   Publications   -   Software I am a postdoctoral fellow in Adam Siepel's computational genomics lab in Cornell University. I received my PhD in Computer Science in 2009 from the CS department at the Technion - Israel Institute of Technology. My PhD avdisor was Shlomo Moran, with whom I continue to enjoy collaborating. I also have a Masters degree in computer science and bioinformatics from the Weizmann Institute of Science (under supervision of Ehud Shapiro).   [ full CV ] Research Interests My research aims to improve our understanding of the evolutionary processes that shape genomes and genomic function, and examine the role of neutral drift and natural selection in this process. The main focus of my work is to develop new computational methods that generate reliable evolutionary inferences from high throughput sequencing data. My methods are based on mathematical models of molecular evolution, population genetics, and phylogenetics, and they are designed and implemented using efficient algorithmic techniques. I am particularly interested in using the computational methods I develop to resolve key open questions in human population genetics and to shed new light on evolution of function in the human genome. I also maintain an active thread of research devoted to theoretical aspects of evolution and algorithms for phylogenetic inference.   [ research projects ] Select Publications Arbiza L, Gronau I, Aksoy BA, Hubisz MJ, Gulko B, Keinan A, Siepel A. Genome-wide inference of natural selection on human transcription factor binding sites. Nature Genetics, accepted April 3, 2013. Gronau I, Arbiza L, Mohammed J, Siepel A. Inference of Natural Selection from Interspersed Genomic Elements Based on Polymorphism and Divergence. Mol Biol Evol, in print, 2013. doi: 10.1093/molbev/mst019 Gronau I, Moran S, Snir S. Fast and Reliable Reconstruction of Phylogenetic Trees with Indistinguishable Edges. Random Struct Alg 40(3):350-384, 2012 * Extended Abstract published in SODA, 2008 Gronau I, Hubisz MJ, Gulko B, Danko CG, Siepel A. Bayesian inference of ancient human demography from individual genome sequences. Nature Genetics 43:1031-1034, 2011 Gronau I, Moran S, Yavneh I. Towards Optimal Distance Functions for Stochastic Substitutions Models. J Theor Biol 260:294-307, 2009   [ all publications ] Featured Software   [ more details ]