Good Lord, what a boring home page! Yes, this is in need of some work, but it always seems to get pushed to the bottom of the to-do list, so it'll likely remain this way for some time to come! Hey, I'm updating it now, aren't I? :)
A bit about me: Currently I'm a graduate student in the field of Genetics and Development in the Molecular Biology and Genetics Department at Cornell. I am just finishing my third year, pretty much have all my course work out of the way (with the exception of a couple small requirements), and am now beginning to push hard to get my thesis project completed.
My research centers around regulatory sequence evolution, and I am currently refining my model for transcription factor binding site turnover, dmotif. Dmotif is a hidden Markov model based on my adviser, Adam Siepel's Dless model, which you can read about here. I have adapted this model to enable detection of transcription factor binding sites under lineage-specific selection, thus extending the model to identify regulatory sequence turnover. The CSHL poster I presented at this year's "Biology of Genomes" meeting is available here. I am currently preparing a manuscript for publication of this work, and will be applying these methods to data from the 24 Mammalian Genomes project this Fall.
I have also participated in a comparative analysis of five Solanacea species. Solanacea are a family of plants that have some unique and attractive properties for comparative genomics. More on this project can be found here.
Dmotif
Dmotif CSHL poster
Solanaceae Project
Contact Adam: agd27@cornell.edu