Possible Papers for BTRY 7200, Topics in Computational Genomics

Ancestral population dynamics, incomplete lineage sorting, complex speciation

Caswell et al. Analysis of chimpanzee history based on genome sequence alignments. PLoS Genet (2008) vol. 4 (4) pp. e1000057 [link]

Pollard et al. Widespread discordance of gene trees with species tree in Drosophila: evidence for incomplete lineage sorting. PLoS Genet (2006) vol. 2 (10) pp. e173 [link]

Patterson et al. Genetic evidence for complex speciation of humans and chimpanzees. Nature (2006) vol. 441 (7097) pp. 1103-8 [link]

Degnan et al. Discordance of species trees with their most likely gene trees. PLoS Genet (2006) vol. 2 (5) pp. e68 [link]

Drummond et al. Bayesian coalescent inference of past population dynamics from molecular sequences. Mol Biol Evol (2005) vol. 22 (5) pp. 1185-92 [link]

Degnan et al. Gene tree distributions under the coalescent process. Evolution (2005) vol. 59 (1) pp. 24-37 [link]

Hudson et al. Mathematical consequences of the genealogical species concept. Evolution (2002) vol. 56 (8) pp. 1557-65 [link]

Coalescent inference

Marjoram et al. Modern computational approaches for analysing molecular genetic variation data. Nat Rev Genet (2006) vol. 7 (10) pp. 759-70 [link]

Kuhner et al. Maximum likelihood estimation of recombination rates from population data. Genetics (2000) vol. 156 (3) pp. 1393-401 [link]

Kuhner et al. Maximum likelihood estimation of population growth rates based on the coalescent. Genetics (1998) vol. 149 (1) pp. 429-34 [link]

Griffiths et al. Ancestral inference from samples of DNA sequences with recombination. J Comput Biol (1996) vol. 3 (4) pp. 479-502 [link]

Kuhner et al. Estimating effective population size and mutation rate from sequence data using Metropolis-Hastings sampling. Genetics (1995) vol. 140 (4) pp. 1421-30 [link]

Gene regulation

Friedman et al. Most mammalian mRNAs are conserved targets of microRNAs. Genome Res (2009) vol. 19 (1) pp. 92-105 [link]

Bourque et al. Evolution of the mammalian transcription factor binding repertoire via transposable elements. Genome Res (2008) vol. 18 (11) pp. 1752-62 [link]

Friedman et al. Ab initio identification of functionally interacting pairs of cis-regulatory elements. Genome Res (2008) vol. 18 (10) pp. 1643-51 [link]

Hon et al. ChromaSig: a probabilistic approach to finding common chromatin signatures in the human genome. PLoS Comput Biol (2008) vol. 4 (10) pp. e1000201 [link]

Linhart et al. Transcription factor and microRNA motif discovery: the Amadeus platform and a compendium of metazoan target sets. Genome Res (2008) vol. 18 (7) pp. 1180-9 [link]

Hawkins et al. The Statistical Power of Phylogenetic Motif Models. LECTURE NOTES IN COMPUTER SCIENCE (2008) [link]

Crombach et al. Evolution of evolvability in gene regulatory networks. PLoS Comput Biol (2008) vol. 4 (7) pp. e1000112 [link]

Siddharthan. PhyloGibbs-MP: module prediction and discriminative motif-finding by Gibbs sampling. PLoS Comput Biol (2008) vol. 4 (8) pp. e1000156 [link]

Zhang et al. Modeling ChIP sequencing in silico with applications. PLoS Comput Biol (2008) vol. 4 (8) pp. e1000158 [link]

Sharon et al. A feature-based approach to modeling protein-DNA interactions. PLoS Comput Biol (2008) vol. 4 (8) pp. e1000154 [link]

Elemento et al. A universal framework for regulatory element discovery across all genomes and data types. Mol Cell (2007) vol. 28 (2) pp. 337-50 [link]

Graphical models

Filiz et al. Graphical models for correlated defaults. Arxiv preprint arXiv:0809.1393 (2008) [link]

Bouchard-Cote et al. Efficient Inference in Phylogenetic InDel Trees. NIPS (2008) [link]

Friston. Hierarchical models in the brain. PLoS Comput Biol (2008) vol. 4 (11) pp. e1000211 [link]

Ray et al. CSMET: comparative genomic motif detection via multi-resolution phylogenetic shadowing. PLoS Comput Biol (2008) vol. 4 (6) pp. e1000090 [link]

Wainwright et al. Graphical Models, Exponential Families, and Variational Inference. Foundations and Trends in Machine Learning (2008) vol. 1 (1-2) pp. 1-305 [link]

Xing et al. Bayesian haplotype inference via the Dirichlet process. J Comput Biol (2007) vol. 14 (3) pp. 267-84 [link]

Lauritzen et al. Graphical Models for Genetic Analyses. STATISTICAL SCIENCE (2003) [link]

Wainwright et al. VARIATIONAL INFERENCE IN GRAPHICAL MODELS: THE VIEW FROM THE MARGINAL POLYTOPE. PROCEEDINGS OF THE ANNUAL ALLERTON CONFERENCE ON ... (2003) [link]

Phylogenetics

Rivas et al. Probabilistic phylogenetic inference with insertions and deletions. PLoS Comput Biol (2008) vol. 4 (9) pp. e1000172 [link]

Drummond et al. BEAST: Bayesian evolutionary analysis by sampling trees. BMC Evol Biol (2007) vol. 7 pp. 214 [link]

Drummond et al. Relaxed phylogenetics and dating with confidence. PLoS Biol (2006) vol. 4 (5) pp. e88 [link]